Five Safes TES
Core Functionality
Five Safes TES is a Weave for the secure, remote execution of GA4GH TES analyses in Trusted Research Environments (TREs).
- TRE managers can register environments, create projects, and manage authorised access.
- Researchers can submit GA4GH TES analyses for secure execution within participating TREs.
Built on international open standards from GA4GH and ELIXIR, Five Safes TES uses an enhanced GA4GH Task Execution Service to receive federated analysis requests. This approach supports the essential disclosure control processes within TREs, ensuring outputs are reviewed to prevent disclosive data from leaving secure environments.
Weave Identity
| Analytical | Data Movement | Data Egress | Initiate | Process |
|---|---|---|---|---|
| Isolated | Summary | Manual | Five Safes TES | TES |
Use in Federated Research
Five Safes TES enables secure cross-TRE federated analytics, where the data remains in place and only the researchers’ analysis code is sent to the data. It is specifically designed to meet the stringent technical and governance constraints of TREs by separating the logical stages of a federated project.